You are watching: Why is protein synthesis different in prokaryotes and eukaryotes

In standard scale protein synthesis wake up in the cytoplasm.
In prokaryotes protein synthesis starts even before the transcription of mRNA molecule is completed. This is called coupledtranscription-translation.
2. Eukaryotic mRNA molecule aremonocistronic, include the coding sequence just for one polypeptide.In prokaryotes individual bacterial mRNA molecules are polycistronic having actually transcripts of number of genes that a details metabolic pathway. (Monocistronic vs polycistronic)3. In eukaryotes, most of the gene have actually introns that separate the actual message for the synthetic of one protein into tiny coding segment referred to as exons.Prokaryotes execute not have introns (ExceptArchaebacteria).4. Eukaryotes: The first amino mountain methionine beginning the ribosome is not formylated. Prokaryotes: The an initial amino mountain methionine is formylated right into N formyl methionine.5.In eukaryotes, the variety of initiating components (IF) is much an ext than prokaryotes.Aboutteninitiating factors(IFs) have been established in reticulocytes an RBC. These space eIF1, eIF2,eIF3,eIF4, eIF5, eIF6 ,eIF4B, eIF4C,eIF4D, eIF4FThreeinitiating determinants found in prokaryotes. PIF-1 , PIF-2 , PIF-3. Discover more:Prokaryotic initiating factorsandEukaryotic initiating factors6. The primary mRNA transcript in eukaryotes undergoes processing and splicing to readjust into a functional mRNA.
In prokaryotes, splicing the mRNA transcript does not occur.7. In eukaryotes, mRNA molecules space modified by the addition of a 5’G cap formed of methylated guanosine triphosphate.No such lid is created at 5’end of bacterial mRNA.
8. In standard scale 5’cap initiates translation by binding mRNA to little ribosomal subunit commonly at the an initial codon AUG.In bacteria translation starts at an AUG codon preceded by a one-of-a-kind nucleotide sequence.9. Apoly A tailformed of around 200 adenin nucleotides is added at the 3’end that mRNA in Eukaryotes.No poly A tail is added to bacterial mRNA.

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10. In eukaryotes tiny subunit of ribosome(40 S) it s okay dissociated v the initatior amino acyl tRNA (Met-tRNA Met) there is no the help of mRNA. The complex joins mRNA later on on.In prokaryotes 30 S subunit an initial complexes through mRNA (30S-mRNA) then joins with f Met tRNA f-Met.Learn more:Difference in between Prokaryotic and Eukaryotic Protein Synthesis