In our recent question and answer, the pharmacist discusses whether or not NyQuil and also ZzzQuil can be taken together.

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Steve asked

Can you take it ZzzQuil and NyQuil together?


It is no safe to take it ZzzQuil v NyQuilas both save sedating "first generation" antihistamines. Making use of both with each other would be taken into consideration a therapeutic duplication and also can increase the risk of next effects.ZzzQuil includes diphenhydramine, the same active ingredient in Benadryl. NyQuil includes doxylamine, also a sedating "first generation" antihistamine.

Interaction in between NyQuil and also ZzzQuilBoth NyQuil and ZzzQuil save on computer sedating, "first generation" antihistamines. Making use of both would be thought about a therapeutic duplication and also increases the risk of next effects.Both drugs cause CNS (central nervous system) depression, i m sorry may an outcome in a to decrease in blood pressure and severe drowsiness. In mix with various other CNS depressants, danger side results such together respiratory depression are possible.Dosing Recommendations

Only take it the NyQuil at bedtime if you need it for trouble sleepingandyou space experiencing multiple cold symptoms. NyQuil is a combination medication that contains the complying with ingredients:

Acetaminophen (analgesic)Dextromethorphan (cough suppressant)Doxylamine (sedating antihistamine)

ZzzQuil consists of only doxylamine as its active ingredient and should usually just be supplied as a sleep assist although it deserve to help details cold symptom such as a runny nose and post sleep drip.

While girlfriend shouldn"t take NyQuil and also ZzzQuil together, you have the right to take DayQuil and also ZzzQuil together.DayQuil includes the following ingredients:

Acetaminophen (analgesic)Dextromethorphan (cough suppressant)Phenylephrine (nasal decongestant)

Taking DayQuil throughout the day and also ZzzQuil in ~ bedtime is safe.


Do no take the ZzzQuil and also Nyquil together because of them both containing a sedating very first generation antihistamine (diphenhydramine and also doxylamine respectively).

It is crucial to note that the is recommended the you carry out not you use sleep aids for an ext than 2 weeks because it can transform your typical sleep patterns. If you still cannot sleep there is no medication ~ the 2 weeks, please contact your doctor. Be certain to always read the ingredient on cold medicine to ensure the you are not taking too much of the same drug or two drugs dealing with the very same symptom.

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Drink plenty of water if on these medications and do no drive or operate machinery while acquisition NyQuil or ZzzQuil.