A insurance claim that the mix of Motrin and Robitussin brand medications causes heart assaults in youngsters has no been developed by reliable clinical evidence.

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Published11 February 2009

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We an initial received an admonition no to incorporate Motrin through Robitussin via email in December 2008:

Medicine interaction!

Madison, period 8, happen away just a couple of days ago. We’ve to be asked to happen this on. Medical professionals told her family members that there have been rather a few children Madison’s age that have died recently the same means that she did. The only usual link in between them was the they were offered Motrin (ibuprofen) and Robitussin together, this caused a heart attack.

They think this is what occurred to them. Castle told she to alert everyone to this. Carry out not give youngsters both the these medications together. Girlfriend can offer them one or the other yet not both.

When Madison broke down she experienced a heart attack and they to be able to revive her yet the ns of oxygen damaged her mind and she was placed on the respirator.

After this she had four strokes prior to she passed away after being taken turn off the respirator. Please pass this on.

The story the warning is framed upon, the an eight-year-old girl called Madison passed away from a love attack and also strokes brought about by this combination of over-the-counter drugs, to be unverifiable: the account listed no information regarding Madison’s surname, where she lived, that her medical professionals were, whereby she to be treated, or even the day she died. Missing any of that information, do the efforts to determine if there in reality was together a child showed a practically impossible task.

It is possible that a child deserve to have a heart attack. Because that example, a news report of 2 October 2007 detailed heart strikes in kids are a rare however under-recognized problem that are many likely brought about by love spasms i beg your pardon briefly cut off the blood supply. It because of this cannot be ruled out that a child called Madison (of no well-known last surname or address) did experience an acute myocardial infarction. However, the in rarely instances youngsters have knowledgeable heart attacks only proves that such occasions happen, no that any details drug interaction causes them.

The active ingredient in children’s Motrin is Ibuprofen, a nonsteroidal anti-inflammatory drug efficient in relieving pain and reducing inflammation. (Ibuprofen is additionally marketed under several various other brand names, such as Advil, Medipren, and also Nuprin.) children Motrin Suspension first became available as a prescription product in 1989, and in 1995 it was cleared by the Food and also Drug management for marketing as an over-the-counter product. Both those landmarks emerged only ~ the product had been generally tested top top children:


Before children’s Motrin came to be an over-the-counter product, its safety profile was supported by a landmark examine involving virtually 84,000 kids — among the largest and also most rigorous children clinical studies ever before conducted. The study spanned 3 years and included 1,735 physicians nationwide.

Robitussin Pediatric cough is a syrup that contains Dextromethorphan HBr, a cough suppressant. That Pediatric sneeze & Cold formulation contains Chlorpheniramine maleate, an antihistamine, in enhancement to the Dextromethorphan HBr.

We have not yet turned up any kind of studies confirming heart assaults brought about by the combination of these two over-the-counter medications, either in children or adults, but that is not to say children should be taking OTC cold medications. An 8 October 2008 declare by the FDA support the referral of the consumer Healthcare commodities Association that youngsters under the period of 4 should not be dosed through over-the-counter cough and cold products. This complies with its January 2008 advisory that these assets not be offered in children under the period of 2 because of the threat of serious and potentially life-threatening next effects.

As noted in a news report native September 2007: “An FDA evaluation of side-effect documents filed through the firm between 1969 and also September 2006 found 54 reports of deaths in children associated with decongestant medications made with pseudoephedrine, phenylephrine or ephedrine. It likewise found 69 reports of deaths linked with antihistamine medicines containing diphenhydramine, brompheniramine or chlorpheniramine. Most of the deaths were youngsters younger than 2.”

The FDA offers these medication tips to the parents and also caregivers of small children:

Do not give kids medications labeled just for adults.Talk to your health treatment professional, such as your physician or pharmacist, if friend have any questions around using cough or cold medications in children.Choose OTC cough and also cold medicines with child-resistant safety caps, when available. After each use, make certain to near the cap tightly and store the medications out the the sight and reach the children.Check the “active ingredients” section of the “Drug Facts” brand of the medicines that friend choose. This ar will assist you know what symptoms the energetic ingredients in the medicine are intended come treat. Cough and also cold medicines frequently have much more than one energetic ingredient, such as an antihistamine, a decongestant, a sneeze suppressant, one expectorant, or a ache reliever and fever reducer.Be really careful if you space giving an ext than one medication to a child. Make certain the drugs do not have the same kind of active ingredients. For example, carry out not offer a child more than one medicine that has a decongestant. If you usage two medicines that have the very same or similar active ingredients, your child could be harmed by gaining too much of one ingredient.Carefully follow the direction for exactly how to usage the medicine in the “Drug Facts” component of the label. These directions call you just how much medicine to give and also how frequently you can provide it. If you have actually a question around how to use the medicine, ask your pharmacist or various other health treatment professional. Overuse or misuse of these products can bring about serious and potentially life-threatening side effects, such as rapid heartbeat, drowsiness, breath problems, and seizures.Only usage measuring devices that come through the medicine or those specially produced measuring drugs. Do not use household spoons come measure drugs for children due to the fact that household spoons come in different sizes and also are not supposed for measure medicines.Understand that using OTC cough and also cold medicines does not cure the cold or cough. These medicines only treat your child’s symptoms, such together runny nose, congestion, fever, and also aches. They do not shorten the length of time your child is sick.

In 2003, another personal account circulated through e-mail implicated children’s Motrin in the development of stomach ulcers in a child dosed through it. Us did no encounter any subsequent reports of comparable instances, and no certain interaction precaution accuse exists because that that drug combination.

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On 22 December 2014, children Medical facility of Dallas addressed the recirculating rumor ~ above Twitter:

If you’ve seen a facebook post around Motrin and Robitussin, you re welcome read and also share this. The info in the short article is not correct and also was not posted by among our employees. Us encourage caregivers to discuss any kind of over-the-counter drugs with their doctor and to ask about information uncovered on the Internet.